Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.50 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.49 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.49 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.49 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15548053 | 0.89 | KDM4E (0.67) | KDM4EMEN1RECQLKMT2APPARG | |
| SCHEMBL16237236 | 0.84 | KDM4E (0.61) | KDM4EMEN1RECQLKMT2APPARG | |
| SCHEMBL8389447 | 0.84 | MEN1 (0.57) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28504148 | 0.84 | KMT2A (0.57) | KDM4EMEN1RECQLKMT2APPARG | |
| Hydrochloric Acid SCHEMBL27537273 | 0.83 | MEN1 (0.56) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL12863966 | 0.83 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APPARG | |
| SCHEMBL15548540 | 0.83 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APPARG | |
| SCHEMBL15547553 | 0.83 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APPARG | |
| SCHEMBL15548642 | 0.83 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APPARG | |
| SCHEMBL15547873 | 0.83 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282732-A | 'alpha'-hydroxy-'beta' amino acid ester and its preparation method | HOFFMANN LA KOCHE & CO AG F (CH) | 2001-02-07 | — | — | CN | disclosed |
| CN-1275567-A | Sulfonate and preparation process thereof | HOFFMANN LA ROCHE (CH) | 2000-12-06 | — | — | CN | disclosed |
| CN-1159185-A | Method for producing beta-amino alcohol | HOFFMANN LA ROCHE (CH) | 1997-09-10 | — | — | CN | disclosed |
| CN-1099387-A | Process for the preparation of beta-aminoalcohols | HOFFMANN LA ROCHE (CH) | 1995-03-01 | — | — | CN | disclosed |