SCHEMBL27544153

SCHEMBL27544153

C=CC(=O)OC(=O)/C(C)=C\C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.48
TSHR P16473 8/20 0.39
HPGD P15428 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37
GLO1 Q04760 1/20 0.36
ALDH1A1 P00352 8/20 0.35
HSD17B10 Q99714 2/20 0.35
LMNA P02545 1/20 0.35
SOAT1 P35610 1/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP3A4 P08684 1/20 0.34
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
CCR6 P51684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7638720 0.87 NPSR1 (0.57) NPSR1HPGDHCAR2GLO1ALDH1A1
SCHEMBL7638724 0.87 NPSR1 (0.57) NPSR1HPGDHCAR2GLO1ALDH1A1
SCHEMBL27601540 0.86 TSHR (0.49) NPSR1TSHRHPGDHCAR2ALDH1A1
SCHEMBL27563806 0.86 NPSR1 (0.44) NPSR1TSHRHPGDHCAR2GLO1
SCHEMBL28177426 0.84 NPSR1 (0.47) NPSR1TSHRHPGDHCAR2GLO1
SCHEMBL28137783 0.83 TSHR (0.64) NPSR1TSHRHPGDHCAR2ALDH1A1
SCHEMBL27660489 0.83 TSHR (0.58) NPSR1TSHRHPGDALDH1A1HSD17B10
SCHEMBL27864576 0.83 ALDH1A1 (0.36) TSHRHPGDALDH1A1HSD17B10TP53
SCHEMBL17079947 0.81 SOAT1 (0.52) NPSR1HPGDHCAR2GLO1ALDH1A1
SCHEMBL1321694 0.81 NPSR1 (0.65) NPSR1TSHRHCAR2GLO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106957392-A The manufacture method that sidewalk for visually impaired people patch hardening resin composition, sidewalk for visually impaired people patch resin combination, sidewalk for visually impaired people patch and sidewalk for visually impaired people are pasted 株式会社菱晃 2017-07-18 CN disclosed
CN-103402765-B Scratch-resistant resin laminate, front plate material for display, and image display device MITSUBISHI PLASTICS INC 2014-12-10 CN disclosed
CN-102523756-B Photosensitive resin composition, and stencil for screen printing using said photosensitive resin composition MURAKAMI CO LTD 2014-11-26 CN disclosed
CN-103522698-A Scratch-resistant resin laminate, front cover material for displays, and image display device MITSUBISHI PLASTICS INC 2014-01-22 CN disclosed
CN-103483853-A Solidified resin composition KONISHI CO LTD 2014-01-01 CN disclosed
CN-103402765-A Scratch-resistant resin laminate, front plate material for display, and image display device MITSUBISHI PLASTICS INC 2013-11-20 CN disclosed
CN-102821737-A Dental adhesive material kit KURARAY MEDICAL INC 2012-12-12 CN disclosed
CN-102523756-A Photosensitive resin composition, and stencil for screen printing using said photosensitive resin composition MURAKAMI CO LTD 2012-06-27 CN disclosed
CN-100591317-C Dental or surgical adhesive and polymerization initiator composition therefor SUN MEDICAL CO LTD 2010-02-24 CN disclosed
CN-100377182-C Thermoreversible recording medium, thermoreversible recording label, thermoreversible recording member, image processing unit and method of image processing RICOH KK (JP) 2008-03-26 CN disclosed
CN-1909870-A Dental or surgical adhesive and polymerization initiator composition therefor SUN MEDICAL CO LTD (JP) 2007-02-07 CN disclosed
CN-1277847-C Paste polymerization initiator composition, dental or surgical adhesive and adhesive kit SUN MEDICAL CO LTD (JP) 2006-10-04 CN disclosed
CN-1659042-A Thermoreversible recording medium, thermoreversible recording mark, thermoreversible recording member, image processing apparatus, and image processing method RICOH KK (JP) 2005-08-24 CN disclosed
CN-1642993-A Polymerization initiator paste composition, dental or surgical adhesive, and adhesive kit SUN MEDICAL CO LTD (JP) 2005-07-20 CN disclosed