Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL275442

N.O=C(O)CCC(NC(C(=O)O)C(=O)O)C(=O)O.[Fe]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.55
NAALAD2 Q9Y3Q0 3/20 0.55
RIMKLA Q8IXN7 1/20 0.55
GGH Q92820 2/20 0.47
TET2 Q6N021 3/20 0.41
KDM4A O75164 2/20 0.41
KDM4C Q9H3R0 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
TET3 O43151 1/20 0.41
CYP1A2 P05177 2/20 0.40
GRM8 O00222 1/20 0.40
GRM6 O15303 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GSR P00390 1/20 0.40
GRIK1 P39086 1/20 0.40
GRM5 P41594 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2245116 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
Ammonia Solution, Strong SCHEMBL2150080 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
Ammonia Solution, Strong SCHEMBL3695091 0.98 FOLH1 (0.57) FOLH1NAALAD2RIMKLAGGHTET2
Ammonia Solution, Strong SCHEMBL3695087 0.98 FOLH1 (0.57) FOLH1NAALAD2RIMKLAGGHTET2
Ammonia Solution, Strong SCHEMBL3695083 0.98 FOLH1 (0.57) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL275407 0.96 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL275405 0.96 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL136061 0.96 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL136060 0.96 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL1653628 0.94 FOLH1 (0.57) FOLH1NAALAD2RIMKLAGGHTET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508200-B1 AQUEOUS FORMULATION CONTAINING 5-AMINOLEVULINIC ACID OR THE LIKE SBI PHARMACEUTICALS CO LTD (JP) 2024-04-10 EP claimed
EP-3168296-B1 AGENT FOR IMPROVING NORMAL DEVELOPMENT RATE OF FERTILIZED EGGS SBI PHARMACEUTICALS CO LTD (JP) 2020-09-09 EP claimed
CN-104487066-B Prophylactic and/or therapeutic agent for radiation damage 国立大学法人东京大学 2020-06-09 CN claimed
US-10675242-B2 Aqueous formulation containing 5-aminolevulinic acid or the like SBI PHARMACEUTICALS, CO., LTD. (JP) 2020-06-09 US claimed
EP-2767278-B1 ENHANCER OF SURVIVAL OF TRANSPLANTED ORGAN SBI PHARMACEUTICALS CO LTD (JP) 2019-11-06 EP claimed
EP-2875812-B1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR RADIATION DAMAGE UNIV TOKYO (JP) 2019-09-04 EP claimed
EP-3508200-A1 AQUEOUS FORMULATION CONTAINING 5-AMINOLEVULINIC ACID OR THE LIKE SBI Pharmaceuticals Co., Ltd. (JP) 2019-07-10 EP claimed
US-20190201336-A1 AQUEOUS FORMULATION CONTAINING 5-AMINOLEVULINIC ACID OR THE LIKE SBI PHARMACEUTICALS, CO., LTD. (JP) 2019-07-04 US claimed
EP-3281642-B1 DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES SBI PHARMACEUTICALS CO LTD (JP) 2019-05-01 EP claimed
EP-1878421-B1 EXTERNAL PREPARATION FOR SKIN SBI PHARMACEUTICALS CO LTD (JP) 2019-04-03 EP claimed
EP-1743621-B1 HAIR RESTORER COSMO OIL CO LTD (JP) 2014-03-05 EP claimed
US-8563605-B2 Therapeutic agent for male sterility SBI PHARMACEUTICALS CO., LTD. (JP) 2013-10-22 US claimed
US-20130011337-A1 THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES SBI PHARMACEUTICALS CO., LTD. (JP) 2013-01-10 US claimed
US-20120122974-A1 HAIR RESTORER COSMO OIL CO., LTD. (JP) 2012-05-17 US claimed
EP-2305237-A1 THERAPEUTIC AGENT FOR MALE STERILITY SBI ALApromo Co., Ltd. (JP) 2011-04-06 EP claimed
US-20110065787-A1 THERAPEUTIC AGENT FOR MALE STERILITY SBI ALApromo., Ltd. 2011-03-17 US claimed
US-20110060042-A1 EXTERNAL PREPARATION FOR SKIN SBI ALAPROMO CO., LTD. (JP) 2011-03-10 US claimed
US-20100120916-A1 THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES SBI ALAPROMO CO., LTD. (JP) 2010-05-13 US claimed
EP-2135613-A1 REMEDY AND DIAGNOSTIC FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASE SBI ALApromo CO., LTD. (JP) 2009-12-23 EP claimed
US-20090130227-A1 EXTERNAL PREPARATION FOR SKIN SBI ALAPROMO CO., LTD. (JP) 2009-05-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10675242-B2 Aqueous formulation containing 5-aminolevulinic acid or the like ALAD, AAAS, SLC7A5 FOLH1 148/4885NAALAD2 1872/4885RIMKLA 209/4885
US-20190201336-A1 AQUEOUS FORMULATION CONTAINING 5-AMINOLEVULINIC ACID OR THE LIKE ALAD, AAAS, SLC7A5 FOLH1 135/4885NAALAD2 2378/4885RIMKLA 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.