⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180158 | 0.79 | — | — | |
| SCHEMBL140291 | 0.75 | — | — | |
| SCHEMBL12305761 | 0.75 | — | — | |
| SCHEMBL7338051 | 0.72 | EGLN1 (0.37) | — | |
| Bromide SCHEMBL28255766 | 0.72 | — | — | |
| SCHEMBL13478061 | 0.72 | CA4 (0.38) | — | |
| SCHEMBL4644763 | 0.72 | — | — | |
| SCHEMBL29087178 | 0.69 | — | — | |
| SCHEMBL17318054 | 0.69 | — | — | |
| SCHEMBL11232653 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3547836-B1 | A PERILLYL ALCOHOL-3 BROMOPYRUVATE CONJUGATE AND METHODS OF TREATING CANCER | UNIV SOUTHERN CALIFORNIA (US) | 2024-08-21 | — | — | EP | claimed |
| CN-110267538-B | Perilla alcohol-3-bromopyruvate conjugates and methods of treating cancer | 尼昂克技术公司 | 2022-04-19 | — | — | CN | claimed |
| US-10858305-B2 | Perillyl alcohol-3-bromopyruvate conjugate and methods of treating cancer | Neonc Technologies, Inc. (US) | 2020-12-08 | — | — | US | claimed |
| US-20190337884-A1 | A PERILLYL ALCOHOL-3-BROMOPYRUVATE CONJUGATE AND METHODS OF TREATING CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA | 2019-11-07 | — | — | US | claimed |
| EP-3547836-A1 | A PERILLYL ALCOHOL-3 BROMOPYRUVATE CONJUGATE AND METHODS OF TREATING CANCER | Neonc Technologies Inc. (US) | 2019-10-09 | — | — | EP | claimed |
| WO-2018102412-A1 | A PERILLYL ALCOHOL-3 BROMOPYRUVATE CONJUGATE AND METHODS OF TREATING CANCER | Neonc Technologies, Inc. (US) | 2018-06-07 | — | — | WO | claimed |
| EP-3547836-B1 | A PERILLYL ALCOHOL-3 BROMOPYRUVATE CONJUGATE AND METHODS OF TREATING CANCER | UNIV SOUTHERN CALIFORNIA (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2022250569-A1 | NOVEL COMPOUND FOR TREATING BILIARY TRACT DISORDERS | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ВАЛЕНТА-ИНТЕЛЛЕКТ" | 2022-12-01 | — | — | WO | disclosed |
| WO-2022250569-A1 | NOVEL COMPOUND FOR TREATING BILIARY TRACT DISORDERS | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ВАЛЕНТА-ИНТЕЛЛЕКТ" | 2022-12-01 | — | — | WO | disclosed |
| CN-110267538-B | Perilla alcohol-3-bromopyruvate conjugates and methods of treating cancer | 尼昂克技术公司 | 2022-04-19 | — | — | CN | disclosed |
| US-10858305-B2 | Perillyl alcohol-3-bromopyruvate conjugate and methods of treating cancer | Neonc Technologies, Inc. (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190337884-A1 | A PERILLYL ALCOHOL-3-BROMOPYRUVATE CONJUGATE AND METHODS OF TREATING CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA | 2019-11-07 | — | — | US | disclosed |
| EP-3547836-A1 | A PERILLYL ALCOHOL-3 BROMOPYRUVATE CONJUGATE AND METHODS OF TREATING CANCER | Neonc Technologies Inc. (US) | 2019-10-09 | — | — | EP | disclosed |
| WO-2007070796-A1 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| EP-1692136-A2 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X-Ceptor Therapeutics, Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056554-A2 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2005-06-23 | — | — | WO | disclosed |
| EP-1532153-A1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X-Ceptor Therapeutics, Inc. (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20050054634-A1 | Modulating active of receptors; therapy prevention of disease such aas symthrome X, antidiabetic agents, insulin resistance, hypoglycemic agents | AKARNA THERAPEUTICS, LTD. (GB) | 2005-03-10 | — | — | US | disclosed |
| US-20040023947-A1 | Azepinoindole and pyridoindole derivatives as pharmaceutical agents | X-CEPTOR THERAPEUTICS INC. | 2004-02-05 | — | — | US | disclosed |
| WO-2003099821-A1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |