SCHEMBL140291

SCHEMBL140291

O=C(Cl)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12305761 1.00
Bromide SCHEMBL28255766 0.96
Methylene Chloride SCHEMBL27901878 0.92
SCHEMBL27886620 0.89
SCHEMBL5267356 0.89 TSHR (0.41)
SCHEMBL29087178 0.83
SCHEMBL10800909 0.78 TRPA1 (0.38)
Tetrahydrofuran SCHEMBL29092140 0.76 ALDH1A1 (0.42)
SCHEMBL27747641 0.75 TSHR (0.37)
SCHEMBL275445 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4574 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036681-A Synthesis method of fluoxastrobin sulfonate intermediate 江苏省农用激素工程技术研究中心有限公司 2026-05-15 CN claimed
US-20260062390-A1 CONTINUOUS FLOW SYNTHESIS OF LORAZEPAM PURDUE RESEARCH FOUNDATION 2026-03-05 US claimed
CN-120137081-A Water-based polymer flow battery positive electrode material, and preparation method and application thereof 浙江大学 2025-06-13 CN claimed
CN-120040302-A Preparation method of salbutamol and salbutamol sulfate 湖北葛店人福药业有限责任公司 2025-05-27 CN claimed
CN-119081363-B PET material for plastic goblets and processing and molding process thereof 惠州市有氧森林环保科技有限公司 2025-04-25 CN claimed
CN-119119629-B Antibacterial functional food packaging film and preparation method thereof 广东爱丽斯包装有限公司 2025-04-15 CN claimed
CN-119798246-A SHP2 targeting fluorescent probe, preparation method and application thereof 山东大学齐鲁医院 2025-04-11 CN claimed
CN-119775997-A Quinoline modified nano white carbon black zinc ion fluorescent probe based on surface imprinting technology and application thereof 江苏海洋大学 2025-04-08 CN claimed
US-20250099407-A1 2-AMINO BENZOPHENONE DERIVATIVES FOR TARGETED FERROPTOSIS INDUCTION IN CANCER THERAPY INDIAN INSTITUTE OF TECHNOLOGY KANPUR (IN) 2025-03-27 US claimed
CN-119570151-A Cold-resistant foaming material for shoe body 磁县宝岛塑胶鞋业有限公司 2025-03-07 CN claimed
WO-2000001678-A1 PROCESS FOR THE SYNTHESIS OF SUBSTITUTED PIPERAZINONES VIA MITSUNOBU REACTION MERCK & CO., INC. (US) 2000-01-13 WO claimed
US-5990126-A 4-HYDROXY-QUINOLIN-2-ONE DERIVATIVES SUBSTITUTED AT POSITION 3 WITH A SUBSTITUTED AROMATIC- OR HETEROAROMATIC-SULFIDE GROUP; ANTAGONIST OF EXCITATORY AMINO ACID FOR NMDA RECEPTORS; TREATING EPILEPSY, STROKE, PARKINSON'S DISEASE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1999-11-23 US claimed
EP-0869122-A1 Quinolinic sulfide derivatives acting as NMDA receptor antagonists and process for preparation thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-10-07 EP claimed
US-5539083-A FROM HALOACETYL HALIDE OR SULFONYLACETYL HALIDE, PROTECTED ALKYLENEDIAMINE, AND A DERIVATIVE OF A NUCLEIC ACID BASE ISIS PHARMACEUTICALS, INC. (US) 1996-07-23 US claimed
CN-1028992-C 1,4-Benzothiazepine derivatives KANEKO NOBORU (JP) 1995-06-21 CN claimed
US-5410060-A Haloacetylation, carboxylation, phosphination BASF AKTIENGESELLSCHAFT (DE) 1995-04-25 US claimed
EP-0019285-B1 PROCESS FOR PREPARING ASYMMETRICAL VAT DYESTUFFS OF THE ANTHRAQUINONE SERIES AND THEIR USE IN DYEING AND PRINTING CIBA-GEIGY AG (CH) 1984-05-09 EP claimed
US-4329456-A ACYLATION WITHOUT INTERMEDIATE ISOLATION CIBA-GEIGY AG (CH) 1982-05-11 US claimed
EP-0019285-A1 Process for preparing asymmetrical vat dyestuffs of the anthraquinone series and their use in dyeing and printing CIBA-GEIGY AG (CH) 1980-11-26 EP claimed
US-3973981-A PHTHALOCYANINE DYES, PAINTS, INKS TOYO INK MANUFACTURING CO., LTD. (JA) 1976-08-10 US claimed