Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CALML3 | P27482 | 1/20 | 0.47 |
| ▸ | SDHA | P31040 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27529025 | 0.81 | SLC6A9 (0.38) | — | |
| SCHEMBL27572993 | 0.75 | AKR1C3 (0.39) | — | |
| SCHEMBL6727353 | 0.74 | MAOB (0.48) | NPC1MAOBLMNAMAOAPTGS1 | |
| SCHEMBL27523437 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL27566328 | 0.70 | F10 (0.39) | NPC1MAOBLMNAMAOAPTGS1 | |
| SCHEMBL27841864 | 0.70 | MAOB (0.47) | NPC1MAOBLMNAMAOAPTGS1 | |
| SCHEMBL2829206 | 0.69 | MAOB (0.72) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL29822424 | 0.69 | MAOB (0.72) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL2829207 | 0.69 | MAOB (0.72) | MAOBLMNAMAOAPTGS1CALML3 | |
| SCHEMBL15793246 | 0.69 | MAOB (0.72) | MAOBLMNAMAOAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1311787-A | oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA CO LTD (SE) | 2001-09-05 | — | — | CN | disclosed |