Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606484 | 0.90 | HTT (0.40) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13266192 | 0.89 | HTT (0.41) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10227064 | 0.84 | HTT (0.42) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13668609 | 0.84 | HTT (0.48) | HTTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL11938362 | 0.83 | NPC1 (0.44) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13266187 | 0.83 | HTT (0.56) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13668610 | 0.83 | HTT (0.44) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10228500 | 0.82 | SLC6A9 (0.39) | HSD11B1MMP2MMP9CNR1GCGR | |
| SCHEMBL10163681 | 0.81 | HTT (0.47) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13953894 | 0.81 | HTT (0.47) | HTTSMN1; SMN2TDP1L3MBTL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088883-B2 | Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-03 | — | — | US | disclosed |