Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592612 | 0.77 | KCNN4 (0.46) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL4298643 | 0.75 | KCNN4 (0.45) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL8895713 | 0.75 | KCNN4 (0.45) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL27566982 | 0.75 | GAA (0.41) | TSHRLMNAALDH1A1KIF11CA2 | |
| SCHEMBL3092500 | 0.75 | KCNN4 (0.45) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL11498640 | 0.75 | KCNN4 (0.45) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL30530487 | 0.75 | KCNN4 (0.45) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL82703 | 0.73 | TSHR (0.44) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL11489146 | 0.73 | KCNN4 (0.43) | KCNN4TSHRLMNACYP19A1HTR2A | |
| SCHEMBL27641406 | 0.73 | KCNN4 (0.43) | KCNN4TSHRLMNACYP19A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308604-A | 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia | AMERICAN HOME PROD (US) | 2001-08-15 | — | — | CN | disclosed |