Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548338 | 0.88 | GAA (0.50) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL11570078 | 0.83 | ALDH1A1 (0.55) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL3047730 | 0.81 | GAA (0.52) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL2259153 | 0.81 | GAA (0.43) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL2259151 | 0.81 | GAA (0.43) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL3047732 | 0.81 | GAA (0.49) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL28082195 | 0.81 | ATM (0.49) | ALDH1A1SMN1; SMN2ACHEMAPTPKM | |
| SCHEMBL11718169 | 0.81 | GAA (0.46) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL29401387 | 0.78 | MAPT (0.55) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 | |
| SCHEMBL2390983 | 0.78 | MAPT (0.55) | GAAALDH1A1SMN1; SMN2HTR2ABCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1289498-C | 1-methylcarbapenem derivatives | SANKYO CO (JP) | 2006-12-13 | — | — | CN | disclosed |
| CN-1486317-A | 1-methylcarbapenem derivatives | ������������ʽ���� | 2004-03-31 | — | — | CN | disclosed |