Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27522567 | 0.87 | TLR8 (0.43) | TLR8ESR1ESR2HTR2A | |
| SCHEMBL27548858 | 0.85 | ADORA3 (0.42) | TLR8ESR1ESR2PTPN1 | |
| SCHEMBL27548745 | 0.85 | ESR1 (0.52) | TLR8ESR1ESR2 | |
| SCHEMBL27548757 | 0.83 | ESR1 (0.53) | TLR8ESR1ESR2 | |
| SCHEMBL27527656 | 0.83 | ADORA3 (0.43) | TLR8ESR1ESR2 | |
| SCHEMBL27548853 | 0.83 | ESR2 (0.44) | TLR8ESR1ESR2HTR2ATAAR1 | |
| SCHEMBL27523677 | 0.80 | ADORA3 (0.46) | TLR8ESR1ESR2 | |
| SCHEMBL27548862 | 0.80 | TSHR (0.42) | TLR8ESR1ESR2HTR2A | |
| SCHEMBL27550312 | 0.79 | GCGR (0.46) | TLR8ESR1ESR2HTR2A | |
| SCHEMBL27747975 | 0.76 | TAAR1 (0.47) | TLR8ESR1ESR2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1291958-C | Naphthacridine derivative and liquid crystal composite containing it | DAINIPPON INK CHEMICAL IND CO (JP) | 2006-12-27 | — | — | CN | disclosed |