⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337066 | 0.74 | — | — | |
| SCHEMBL805280 | 0.67 | — | — | |
| SCHEMBL28833403 | 0.67 | — | — | |
| SCHEMBL18360940 | 0.67 | — | — | |
| SCHEMBL8061141 | 0.67 | — | — | |
| SCHEMBL3111439 | 0.65 | — | — | |
| SCHEMBL11612430 | 0.65 | — | — | |
| SCHEMBL371431 | 0.65 | — | — | |
| SCHEMBL9999127 | 0.63 | — | — | |
| SCHEMBL2713684 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793559-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-03-24 | — | — | EP | disclosed |
| EP-2136799-B1 | MACROCYCLIC COMPOUNDS USEFUL AS INHIBITORS OF KINASES AND HSP90 | UNIV STRASBOURG (FR) | 2017-10-04 | — | — | EP | disclosed |
| US-9765089-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170166545-A1 | METHODS FOR PRODUCING BERAPROST AND ITS DERIVATIVES | LUNG BIOTECHNOLOGY PBC (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170095458-A1 | HETEROARYL SULFONAMIDES AND CCR2/CCR9 | CHEMOCENTRYX, INC. (US) | 2017-04-06 | — | — | US | disclosed |
| US-9540331-B2 | Preparation method of dexmedetomidine intermediate | TIANJIN WEIJIE PHARMACEUTICAL CO., LTD (CN) | 2017-01-10 | — | — | US | disclosed |
| WO-2017000277-A1 | SUBSTITUTED TRIAZOLO BICYCLICCOMPOUNDS AS PDE2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-01-05 | — | — | WO | disclosed |
| WO-2017003894-A1 | SUBSTITUTED TRIAZOLO BICYCLIC COMPOUNDS AS PDE2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-01-05 | — | — | WO | disclosed |
| WO-2016200851-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC. (US) | 2016-12-15 | — | — | WO | disclosed |
| US-20160272594-A1 | PREPARATION METHOD OF DEXMEDETOMIDINE INTERMEDIATE | TIANJIN WEIJIE PHARMACEUTICAL CO., LTD (CN) | 2016-09-22 | — | — | US | disclosed |
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| US-20030050330-A1 | 4,5-subtstituted imdazolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. | 2003-03-13 | — | — | US | disclosed |
| EP-0772601-B1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6426360-B1 | ANTIARTHRITIC AGENTS | G D SEARLE & CO. | 2002-07-30 | — | — | US | disclosed |
| EP-1211244-A2 | 4,5-substitued imidazolyl compounds for the treatment of inflammation | G.D. Searle & Co. (US) | 2002-06-05 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-6232319-B1 | TREATMENT OF MEMORY DEFECTS ASSOCIATED WITH CEREBRAL AGING AND WITH NEURODEGENERATIVE DISEASES INCLUDING ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, PICK'S DISEASE, KORSAKOFF'S DISEASE AND FRONTAL AND SUBCOTICAL DEMENTIAS | ADIR ET COMPAGNIE (FR) | 2001-05-15 | — | — | US | disclosed |
| US-5936097-A | ANTITUMOR AGENTS | RHONE-POULENC RORER, S.A. (FR) | 1999-08-10 | — | — | US | disclosed |
| US-5616714-A | PYRIDYL, THIAZOLYL-SUBSTITUTED AMINO ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-04-01 | — | — | US | disclosed |
| US-5521175-A | CHOLECYSTOKININS AND GASTRIN ANTAGONIST FOR PHYSIOLOGICAL DISORDERS | MERCK SHARP & DOHME LTD. (GB) | 1996-05-28 | — | — | US | disclosed |