Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703132 | 0.81 | BACE1 (0.35) | MEN1KMT2ANPC1 | |
| SCHEMBL27267001 | 0.81 | KMT2A (0.35) | MEN1KMT2APOLB | |
| SCHEMBL27265076 | 0.77 | PNMT (0.39) | MEN1KMT2A | |
| SCHEMBL27259036 | 0.76 | USP2 (0.45) | MEN1KMT2APOLBNPC1 | |
| SCHEMBL27265499 | 0.76 | KMT2A (0.44) | MEN1KMT2APOLBNPC1 | |
| SCHEMBL28140790 | 0.75 | ESR1 (0.49) | CYP19A1CYP11B1ESR1ESR2DRD2 | |
| SCHEMBL27268335 | 0.73 | — | — | |
| SCHEMBL27523226 | 0.72 | ESR1 (0.43) | CYP19A1CYP11B1ESR1ESR2MAOA | |
| SCHEMBL27769841 | 0.72 | CYP19A1 (0.30) | CYP19A1MAOAMAOBDYRK1A | |
| SCHEMBL28141495 | 0.68 | ESR2 (0.49) | CYP19A1ESR1ESR2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710438-A | Spirocyclic compound for promoting generation of iPS cells, and preparation method and use thereof | SHANGHAI INST MATERIA MEDICA | 2015-06-17 | — | — | CN | disclosed |
| CN-1166638-C | Novel benzo-[3,4] cyclobutano [1,2-C] pyrroles compound, its prepn. and medicine composition containing the same | ɪά��ʵ���� | 2004-09-15 | — | — | CN | disclosed |
| CN-1274718-A | Novel benzo-[3,4] cyclobutano [1,2-C] pyrroles compound, its prepn. and medicine composition containing the same | ADIR (FR) | 2000-11-29 | — | — | CN | disclosed |