Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | CETP | P11597 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27493742 | 0.87 | AR (0.36) | ARCETPCA1CA2KIF11 | |
| Ethoxycarbonyl Group SCHEMBL27550175 | 0.87 | AR (0.36) | ARCETPCA1CA2KIF11 | |
| SCHEMBL26989692 | 0.87 | AR (0.40) | ARCA1CA2KIF11CHRNB2 | |
| SCHEMBL17504397 | 0.87 | AR (0.40) | ARCA1CA2KIF11CHRNB2 | |
| SCHEMBL29740491 | 0.87 | AR (0.40) | ARCA1CA2KIF11CHRNB2 | |
| SCHEMBL1058695 | 0.87 | AR (0.40) | ARCA1CA2KIF11CHRNB2 | |
| SCHEMBL30716841 | 0.87 | AR (0.40) | ARCA1CA2KIF11CHRNB2 | |
| SCHEMBL27550612 | 0.86 | CA1 (0.34) | ARCETPCA1CA2KIF11 | |
| Propylformate SCHEMBL27569704 | 0.85 | AR (0.35) | ARCETPCA1CA2KIF11 | |
| SCHEMBL27578197 | 0.83 | PNMT (0.34) | CETPCA1CA2KIF11CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1318057-A | 4-amino substituted-2-substituted-1, 2,3, 4-tetrahydroquinolines as CETP inhibitors | PFIZER PROD INC (US) | 2001-10-17 | — | — | CN | claimed |
| CN-1515259-A | 4-aminosubstituted-2-substituted-1,2,3,4-tetrahydroquinoline used as CETP inhibitor | �������Զ�˹�Ʒ� | 2004-07-28 | — | — | CN | disclosed |
| CN-1318057-A | 4-amino substituted-2-substituted-1, 2,3, 4-tetrahydroquinolines as CETP inhibitors | PFIZER PROD INC (US) | 2001-10-17 | — | — | CN | disclosed |