Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.45 |
| ▸ | NOS1 | P29475 | 4/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | USP9X | Q93008 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25108316 | 0.86 | IDO1 (0.60) | IDO1TRPV1NOS1AXLUSP9X | |
| SCHEMBL23021781 | 0.80 | IDO1 (0.60) | IDO1TRPV1NOS1AXLJAK2 | |
| SCHEMBL1760367 | 0.80 | IDO1 (0.47) | IDO1TRPV1NOS1AXLJAK2 | |
| SCHEMBL30162490 | 0.78 | IDO1 (0.55) | IDO1TRPV1NOS1AXLJAK2 | |
| SCHEMBL2611042 | 0.76 | IDO1 (0.55) | IDO1TRPV1NOS1AXLJAK2 | |
| SCHEMBL28592498 | 0.73 | IDO1 (0.53) | IDO1TRPV1NOS1AXLJAK2 | |
| SCHEMBL20353958 | 0.73 | IDO1 (0.53) | IDO1TRPV1NOS1AXLJAK2 | |
| SCHEMBL22079091 | 0.73 | IDO1 (0.53) | IDO1TRPV1NOS1AXLJAK2 | |
| SCHEMBL22121496 | 0.73 | IDO1 (0.46) | IDO1TRPV1NOS1JAK2JAK1 | |
| SCHEMBL24368019 | 0.71 | IDO1 (0.54) | IDO1TRPV1NOS1AXLJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274670-C | Diaminopropionic acid derivatives | HOFFMANN LA ROCHE (CH) | 2006-09-13 | — | — | CN | disclosed |
| CN-1323291-A | Diaminopropionic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | disclosed |