Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 0.71 |
| ▸ | HTR3A | P46098 | 20/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27846478 | 0.86 | HTR1A (0.50) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14734867 | 0.84 | HTR1A (1.00) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27549245 | 0.82 | HTR1A (0.66) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL546684 | 0.81 | HTR1A (1.00) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL547488 | 0.81 | HTR1A (0.77) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL546723 | 0.81 | HTR1A (0.78) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL547068 | 0.81 | HTR1A (1.00) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL546677 | 0.81 | HTR1A (0.77) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| Bromide SCHEMBL20360588 | 0.80 | HTR1A (0.97) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL547714 | 0.80 | HTR1A (1.00) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1319958-C | Phenyl piperazine derivatives as serotonin reuptake inhibitors | LUNDBECK & CO AS H (DK) | 2007-06-06 | — | — | CN | claimed |
| CN-1561336-A | Phenyl-piperazine derivatives as serotonin reuptake inhibitors | LUNDBECK & CO AS H (DK) | 2005-01-05 | — | — | CN | claimed |
| CN-1319958-C | Phenyl piperazine derivatives as serotonin reuptake inhibitors | LUNDBECK & CO AS H (DK) | 2007-06-06 | — | — | CN | disclosed |
| CN-1561336-A | Phenyl-piperazine derivatives as serotonin reuptake inhibitors | LUNDBECK & CO AS H (DK) | 2005-01-05 | — | — | CN | disclosed |