Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476846 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL27476847 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL27477277 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL5425216 | 0.77 | KMT2A (0.60) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL6865331 | 0.77 | KMT2A (0.60) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL27479371 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL12050587 | 0.74 | TSHR (0.59) | ALDH1A1TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL25593840 | 0.74 | KMT2A (0.59) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL7501113 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL27398774 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1191245-C | Substituted cyclobutylamine derivatives | DAIICHI PHARMACEUTIAL CO LTD (JP) | 2005-03-02 | — | — | CN | disclosed |
| CN-1265659-A | Substituted cyclobutylamine derivatives | DAIICHI PHARMACEUTIAL CO LTD (JP) | 2000-09-06 | — | — | CN | disclosed |