Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27494327 | 0.90 | NPY1R (0.50) | NPY1RALDH1A1MAPTTP53HSD17B10 | |
| SCHEMBL27494317 | 0.84 | NPY1R (0.60) | NPY1RTP53 | |
| SCHEMBL27478238 | 0.82 | NPY1R (0.51) | NPY1R | |
| SCHEMBL27493923 | 0.80 | NPY1R (0.66) | NPY1RSMN1; SMN2 | |
| SCHEMBL27476950 | 0.80 | NPY1R (0.52) | NPY1RALDH1A1TP53GAAKMT2A | |
| SCHEMBL27479802 | 0.79 | NPY1R (0.51) | NPY1RALDH1A1GAA | |
| SCHEMBL7958736 | 0.78 | NPY1R (0.71) | NPY1RALDH1A1TP53GAAHSD17B10 | |
| SCHEMBL27479056 | 0.77 | NPY1R (0.47) | NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL27479801 | 0.76 | NPY1R (0.53) | NPY1RALDH1A1TP53GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27478640 | 0.76 | NPY1R (0.48) | NPY1RALDH1A1MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |