Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 12/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963219 | 0.90 | NPY1R (0.75) | NPY1RHSD17B10KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7956905 | 0.87 | NPY1R (0.83) | NPY1RKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL8802019 | 0.86 | NPY1R (0.71) | NPY1RHSD17B10TP53KMT2AALDH1A1 | |
| SCHEMBL7949187 | 0.83 | NPY1R (0.79) | NPY1RKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7963164 | 0.83 | NPY1R (1.00) | NPY1RKMT2ASMN1; SMN2 | |
| SCHEMBL7959050 | 0.83 | NPY1R (0.87) | NPY1RTP53KMT2ASMN1; SMN2 | |
| SCHEMBL7956724 | 0.81 | NPY1R (0.75) | NPY1RTP53KMT2A | |
| SCHEMBL7958925 | 0.80 | NPY1R (0.71) | NPY1RKMT2A | |
| SCHEMBL7958879 | 0.79 | NPY1R (0.61) | NPY1RGAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7959104 | 0.79 | NPY1R (0.73) | NPY1RKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |