SCHEMBL27552170

SCHEMBL27552170

O=Cc1cccc2nnn(O)c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
POLB P06746 1/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 1/20 0.44
ERN1 O75460 4/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TRIM24 O15164 2/20 0.35
TRIM33 Q9UPN9 2/20 0.35
NPC1 O15118 1/20 0.33
HSP90AA1 P07900 1/20 0.33
IDO1 P14902 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9524068 0.79 SLC9A1 (0.44) KDM4EATMERN1LMNAMEN1
SCHEMBL2149335 0.73 POLB (0.50) KDM4EPOLBMAPK1ATMLMNA
SCHEMBL28390322 0.72 KDM4E (0.49) KDM4EPOLBMAPK1ATMLMNA
SCHEMBL13730894 0.72 KDM4E (0.49) KDM4EPOLBMAPK1ATMLMNA
SCHEMBL3282387 0.72 KDM4E (0.49) KDM4EPOLBMAPK1ATMLMNA
SCHEMBL6274820 0.71 KDM4E (0.45) KDM4EPOLBMAPK1ATMLMNA
SCHEMBL5921930 0.71 KDM4E (0.45) KDM4EPOLBMAPK1ATMLMNA
SCHEMBL10085250 0.70 TDP1 (0.56) LMNAMAPTMEN1KMT2ATDP1
SCHEMBL5921928 0.70 KDM4E (0.44) KDM4EPOLBMAPK1ATMLMNA
SCHEMBL31464931 0.69 FGFR1 (0.47) KDM4EPOLBMAPK1ATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101209987-A Thermosetting resin composition containing maleimide and/or vinyl compound HENKEL CORP (US) 2008-07-02 CN disclosed
CN-1158607-A Thermosetting resin composition containing maleimide and/or vinyl compound QUANTUM MATERIALS INC (US) 1997-09-03 CN disclosed