Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466733 | 0.78 | HDAC8 (0.38) | SLC6A4SLC6A3 | |
| SCHEMBL27482760 | 0.77 | HPGD (0.33) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27466234 | 0.74 | GCK (0.33) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27481680 | 0.74 | HRH3 (0.35) | — | |
| SCHEMBL27484543 | 0.73 | SLC6A4 (0.31) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27483145 | 0.72 | HTR2A (0.44) | SLC6A3 | |
| SCHEMBL27582670 | 0.70 | MRGPRX4 (0.33) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27467636 | 0.66 | HDAC8 (0.36) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27643867 | 0.65 | IDO1 (0.32) | — | |
| SCHEMBL19749365 | 0.62 | SLC6A2 (0.46) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |