Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 4/20 | 0.47 |
| ▸ | BCR | P11274 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448761 | 0.85 | PARP1 (0.61) | PARP1ABL1BCRDYRK1ARIPK1 | |
| SCHEMBL711132 | 0.85 | PARP1 (0.61) | PARP1ABL1BCRDYRK1ARIPK1 | |
| Hydrochloric Acid SCHEMBL1268771 | 0.83 | PARP1 (0.59) | PARP1ABL1BCRDYRK1ARIPK1 | |
| SCHEMBL27629715 | 0.80 | THRA (0.53) | SMPD1PCSK9 | |
| SCHEMBL203104 | 0.79 | SMPD1 (0.68) | PARP1SMPD1PLA2G4B | |
| Trifluoroacetic Acid SCHEMBL12480668 | 0.79 | PARP1 (0.54) | PARP1ABL1BCRDYRK1ARIPK1 | |
| SCHEMBL19707300 | 0.79 | THRA (0.51) | PCSK9DDR1HDAC8 | |
| SCHEMBL12951117 | 0.78 | SMPD1 (0.70) | PARP1SMPD1PLA2G4B | |
| SCHEMBL201242 | 0.78 | SMPD1 (0.70) | PARP1SMPD1PLA2G4B | |
| SCHEMBL202638 | 0.78 | SMPD1 (0.70) | PARP1SMPD1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188394-A | Arthropodicidal and fungicidal cyclic amides | DU PONT (US) | 1998-07-22 | — | — | CN | disclosed |