Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Pyrazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazole SCHEMBL9012286 | 0.97 | — | — | |
| Pyrazole SCHEMBL27984995 | 0.95 | — | — | |
| Pyrazole SCHEMBL26122185 | 0.91 | — | — | |
| Pyrazole SCHEMBL25401896 | 0.88 | — | — | |
| Pyrazole SCHEMBL27617303 | 0.85 | NQO2 (0.33) | — | |
| Pyrazole SCHEMBL28302306 | 0.84 | — | — | |
| Pyrazole SCHEMBL18227431 | 0.84 | — | — | |
| Pyrazole SCHEMBL1236436 | 0.84 | — | — | |
| Pyrazole SCHEMBL1800516 | 0.84 | — | — | |
| Pyrazole SCHEMBL1559259 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184473-A | 6-Hydroxyamide-Dihydropyran Derivatives | BIOTA SCIENT MANAGEMENT (AU) | 1998-06-10 | — | — | CN | disclosed |