Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | PPARD | Q03181 | 7/20 | 0.53 |
| ▸ | PPARA | Q07869 | 7/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL27306756 | 1.00 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL28862269 | 0.88 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL28136494 | 0.87 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL7768893 | 0.87 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL11441774 | 0.87 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL28135719 | 0.87 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL28416062 | 0.87 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL8210441 | 0.87 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL11803275 | 0.87 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL27760611 | 0.86 | KDM4E (0.42) | TDP1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1536015-A | Composite thermal stabilizing agent for polyvinyl chloride and its derivative composition | 深圳市海川实业股份有限公司 | 2004-10-13 | — | — | CN | claimed |
| CN-102449067-B | Polycarbonate resin composition and molded article comprising same | IDEMITSU KOSAN CO | 2015-05-06 | — | — | CN | disclosed |
| CN-104212149-A | Polycarbonate resin composition and molded article comprising same | IDEMITSU KOSAN CO | 2014-12-17 | — | — | CN | disclosed |
| CN-102449067-A | Polycarbonate resin composition and molded article comprising same | IDEMITSU KOSAN CO | 2012-05-09 | — | — | CN | disclosed |
| CN-101248128-B | Coordination polymeric triethanolamine perchloric acid (triflato) metal inner complexes as additives for synthetic polymers | CATENA ADDITIVES GMBH & CO KG | 2012-05-09 | — | — | CN | disclosed |
| CN-101248128-A | Coordination polymeric triethanolamine perchloric acid (triflato) metal inner complexes as additives for synthetic polymers | CATENA ADDITIVES GMBH & CO KG (DE) | 2008-08-20 | — | — | CN | disclosed |
| CN-1333009-C | Composite thermal stabilizing agent for polyvinyl chloride and its derivative composition | HAICHUAN IND CO LTD (CN) | 2007-08-22 | — | — | CN | disclosed |
| CN-1536015-A | Composite thermal stabilizing agent for polyvinyl chloride and its derivative composition | 深圳市海川实业股份有限公司 | 2004-10-13 | — | — | CN | disclosed |