Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | CYBB | P04839 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797209 | 0.88 | NOX1 (0.43) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1509895 | 0.83 | NOX1 (0.46) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1509731 | 0.79 | NOX1 (0.47) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL28373803 | 0.77 | NOX1 (0.55) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1856711 | 0.74 | NOX1 (0.47) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL4904429 | 0.73 | NOX1 (0.56) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL17284839 | 0.72 | NOX1 (0.71) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1853045 | 0.72 | NOX1 (0.47) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL4670419 | 0.72 | NOX1 (0.43) | NOX1GAAMAPTMEN1ALOX15 | |
| Phenothiazine SCHEMBL688772 | 0.72 | NOX1 (0.63) | NOX1GAAMAPTMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1284777-C | 5-membered heterocycles, preparation and use thereof as medicine | SOD CONSEILS RECH APPLIC (FR) | 2006-11-15 | — | — | CN | disclosed |
| CN-1535267-A | 5-membered heterocycles, preparation and use thereof as medicine | ��ѧ�о���Ӧ����ѯ��˾ | 2004-10-06 | — | — | CN | disclosed |