Phenothiazine

Phenothiazine

SCHEMBL688772

CCC(=O)O.c1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.63
GAA P10253 8/20 0.63
MAPT P10636 7/20 0.63
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
ALOX15 P16050 3/20 0.63
SNCA P37840 3/20 0.63
TDP1 Q9NUW8 3/20 0.63
BCHE P06276 2/20 0.63
ACHE P22303 2/20 0.63
CYP1A2 P05177 1/20 0.63
POLB P06746 1/20 0.63
CYP3A4 P08684 1/20 0.63
ADORA3 P0DMS8 1/20 0.63
ALOX12 P18054 1/20 0.63
MAOA P21397 1/20 0.63
CNR1 P21554 1/20 0.63
PTGS1 P23219 1/20 0.63
SLC6A2 P23975 1/20 0.63
HTR2C P28335 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL28750254 0.86 NOX1 (0.71) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL10627587 0.85 NOX1 (0.63) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL8158378 0.85 NOX1 (0.68) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL9347283 0.82 NOX1 (0.85) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL17289208 0.81 NOX1 (0.68) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL7978596 0.80 NOX1 (0.74) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL1509832 0.80 NOX1 (0.74) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL9715033 0.80 NOX1 (0.64) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL6315328 0.79 NOX1 (1.00) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL9114 0.79 NOX1 (1.00) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1625411-A Combination of a NSAID and a PDE-4 inhibitor ALTANA PHARMA AG (DE) 2005-06-08 CN claimed
EP-1799816-B1 NOVEL LACCASE ENZYME AND USE THEREOF AB ENZYMES OY (FI) 2015-08-19 EP disclosed
EP-1799815-B1 NOVEL LACCASE ENZYMES AND THEIR USES AB ENZYMES OY (FI) 2012-02-29 EP disclosed
CN-101023166-B Novel laccase enzymes and their uses AB ENZYMES OY 2011-08-24 CN disclosed
CN-101023165-B Novel laccase enzyme and application thereof AB ENZYMES OY 2011-08-24 CN disclosed
US-7927849-B2 Laccase enzyme and use thereof AB ENZYMES OY (FI) 2011-04-19 US disclosed
US-7732178-B2 Laccase enzymes and their uses AB ENZYMES OY (FI) 2010-06-08 US disclosed
CN-100496607-C Combination of a NSAID and a PDE-4 inhibitor ALTANA PHARMA AG (DE) 2009-06-10 CN disclosed
US-20080248016-A1 Novel Iaccase Enzymes and Their Uses AB ENZYMES OY (FI) 2008-10-09 US disclosed
CN-101023166-A Novel laccase enzymes and their uses AB ENZYMES OY (FI) 2007-08-22 CN disclosed
EP-1799815-A2 NOVEL LACCASE ENZYMES AND THEIR USES AB Enzymes Oy (FI) 2007-06-27 EP disclosed
CN-1267087-C Pharmaceutical tablet PHARMACIA CORP (US) 2006-08-02 CN disclosed
WO-2006032724-A2 NOVEL LACCASE ENZYMES AND THEIR USES AB ENZYMES OY (FI) 2006-03-30 WO disclosed
WO-2006032723-A1 NOVEL LACCASE ENZYME AND USE THEREOF AB ENZYMES OY (FI) 2006-03-30 WO disclosed
US-20060063246-A1 Novel laccase enzyme and use thereof AB ENZYMES OY (FI) 2006-03-23 US disclosed
CN-1630512-A Pharmaceutical tablet PHARMACIA CORP (US) 2005-06-22 CN disclosed
CN-1625411-A Combination of a NSAID and a PDE-4 inhibitor ALTANA PHARMA AG (DE) 2005-06-08 CN disclosed
CN-1456680-A Multi-layer reagent strips and method for measuring saccharfied protein in physiological samples LIFE SCANNING CORP (US) 2003-11-19 CN disclosed
CN-1254369-A Cleaning compositions comprising xylan degrading alkaline enzyme and bleaching agent PROCTER & GAMBLE (US) 2000-05-24 CN disclosed
CN-1233278-A Detergent compositions comprising antibody controlled enzymatic activity PROCTER & GAMBLE (US) 1999-10-27 CN disclosed