⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651514 | 1.00 | — | — | |
| SCHEMBL27651515 | 1.00 | — | — | |
| SCHEMBL3630003 | 0.81 | — | — | |
| SCHEMBL6953341 | 0.81 | — | — | |
| SCHEMBL27637609 | 0.72 | — | — | |
| SCHEMBL30620063 | 0.71 | — | — | |
| SCHEMBL709727 | 0.71 | — | — | |
| SCHEMBL27666531 | 0.71 | — | — | |
| SCHEMBL27630902 | 0.71 | — | — | |
| SCHEMBL27842331 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809557-B | Compound | ASTRAZENECA AB | 2012-07-04 | — | — | CN | claimed |
| CN-101437811-A | Quinoline derivatives | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| CN-101437810-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| CN-101437812-A | Quinoline derivatives for the treatment of cancer | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | claimed |
| CN-101432276-A | Quinoline derivatives | ASTRAZENECA AB (SE) | 2009-05-13 | — | — | CN | claimed |
| CN-101341133-A | Quinazoline derivatives, process for their preparation and their use as anti-cancer agents | ASTRAZENECA AB (SE) | 2009-01-07 | — | — | CN | claimed |
| CN-100415724-C | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2008-09-03 | — | — | CN | claimed |
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | claimed |
| CN-100354278-C | Quinazoline derivatives as SRC tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2007-12-12 | — | — | CN | claimed |
| CN-100347169-C | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2007-11-07 | — | — | CN | claimed |
| CN-100345844-C | Quinazoline derivatives for the treatment of tumours | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | claimed |
| CN-100343238-C | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB (SE) | 2007-10-17 | — | — | CN | claimed |
| CN-1735617-A | Quinazoline derivatives as SRC tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2006-02-15 | — | — | CN | claimed |
| CN-1471527-A | Quinazoline derivatives | — | 2004-01-28 | — | — | CN | claimed |
| CN-1434821-A | Quinazoline derivatives for the treatment of tumours | ASTRAZENECA AB (SE) | 2003-08-06 | — | — | CN | claimed |
| CN-1378537-A | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2002-11-06 | — | — | CN | claimed |
| CN-1360582-A | Quinazoline derivs. | ASTRAZENECA UK LTD (GB) | 2002-07-24 | — | — | CN | claimed |
| CN-101072758-B | Quinazoline derivatives | ASTRAZENECA AB | 2013-07-31 | — | — | CN | disclosed |
| CN-1360582-A | Quinazoline derivs. | ASTRAZENECA UK LTD (GB) | 2002-07-24 | — | — | CN | disclosed |
| CN-1344256-A | (Hetero) aryl-bicyclic heteroaryl derivatives, their prepn. and their use as protease inhibitors | AXYS PHARM INC (US) | 2002-04-10 | — | — | CN | disclosed |