Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727762 | 0.73 | TSHR (0.35) | ALDH1A1RAB9ANPC1MAPK1NOTUM | |
| SCHEMBL335769 | 0.73 | TSHR (0.35) | ALDH1A1RAB9ANPC1MAPK1NOTUM | |
| SCHEMBL985249 | 0.71 | — | — | |
| Iodide SCHEMBL8897376 | 0.71 | ESR1 (0.33) | ALDH1A1RAB9ANPC1MAPK1ESR1 | |
| SCHEMBL29573169 | 0.71 | ESR1 (0.33) | ALDH1A1RAB9ANPC1MAPK1ESR1 | |
| Lithium Ion SCHEMBL1450620 | 0.69 | — | — | |
| SCHEMBL1450842 | 0.69 | — | — | |
| SCHEMBL11113450 | 0.69 | ALDH1A1 (0.37) | ALDH1A1RAB9ANPC1MAPK1NOTUM | |
| SCHEMBL7859080 | 0.69 | ESR1 (0.32) | ALDH1A1ESR1ESR2LTA4HTSHR | |
| SCHEMBL6969030 | 0.69 | ESR1 (0.32) | ALDH1A1ESR1ESR2LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1290275-A | Catalyst and process for polymerization of cycloolefin | GOODRICH CO B F (US) | 2001-04-04 | — | — | CN | disclosed |