Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994629 | 1.00 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL993580 | 1.00 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL26961108 | 0.77 | HDAC1 (0.68) | L3MBTL1ALDH1A1 | |
| SCHEMBL6264887 | 0.76 | TTR (0.58) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL22887384 | 0.76 | TTR (0.58) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL993581 | 0.75 | KDR (0.64) | MEN1KMT2AKDRCES1KDM4E | |
| SCHEMBL22887383 | 0.75 | P4HB (0.53) | MEN1KMT2ANPC1RAB9AKDR | |
| SCHEMBL8302747 | 0.75 | P4HB (0.53) | MEN1KMT2ANPC1RAB9AKDR | |
| SCHEMBL29496343 | 0.75 | P4HB (0.53) | MEN1KMT2ANPC1RAB9AKDR | |
| SCHEMBL8302760 | 0.75 | P4HB (0.53) | MEN1KMT2ANPC1RAB9AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285578-C | Substituted benzoic acid amides and their use in inhibiting angiogenesis | SCHERING AG (DE) | 2006-11-22 | — | — | CN | disclosed |
| CN-1426396-A | Substituted benzoic acid amides and use for inhibition of angiogenesis thereof | SCHERING AG (DE) | 2003-06-25 | — | — | CN | disclosed |