Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244885 | 0.84 | NPSR1 (0.69) | NPSR1MMEACEACE2MMP1 | |
| SCHEMBL12863002 | 0.84 | NPSR1 (0.69) | NPSR1MMEACEACE2MMP1 | |
| SCHEMBL17468460 | 0.84 | NPSR1 (0.69) | NPSR1MMEACEACE2MMP1 | |
| SCHEMBL27540746 | 0.84 | NPSR1 (0.52) | NPSR1MMEACEACE2CTSS | |
| SCHEMBL684246 | 0.83 | NPSR1 (0.55) | NPSR1MMEACEACE2CTSS | |
| SCHEMBL683352 | 0.83 | NPSR1 (0.55) | NPSR1MMEACEACE2CTSS | |
| SCHEMBL28376588 | 0.83 | CTSS (0.61) | CTSSCTSKPAMNPC1RAB9A | |
| SCHEMBL28376590 | 0.83 | CTSS (0.61) | CTSSCTSKPAMNPC1RAB9A | |
| SCHEMBL12862963 | 0.82 | NPSR1 (0.54) | NPSR1MMEACEACE2MMP1 | |
| SCHEMBL7942092 | 0.81 | NPSR1 (0.50) | NPSR1MMEACEACE2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1289333-A | Oxazole derivatives as serotonin-1A receptor ogonists | AMERICAN HOME PROD (US) | 2001-03-28 | — | — | CN | disclosed |