Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutane SCHEMBL27557774 | 0.84 | PHGDH (0.42) | BRD4MAPTPHGDHPTGS2 | |
| Isobutane SCHEMBL27643374 | 0.81 | PHGDH (0.32) | SYKBRD4HRH3MAPTKMT2A | |
| SCHEMBL27624100 | 0.80 | HTT (0.35) | ENPP1BRD4HRH3NMT1KDM4E | |
| Isobutane SCHEMBL27557800 | 0.76 | SYK (0.43) | SYKENPP1BRD4HRH3NMT1 | |
| Isobutane SCHEMBL27538682 | 0.75 | SYK (0.43) | SYKENPP1BRD4HRH3NMT1 | |
| SCHEMBL1925748 | 0.69 | NR1H2 (0.39) | KDM4EHTTSMN1; SMN2PTGS2 | |
| SCHEMBL27558031 | 0.69 | NR1H2 (0.38) | SYKATMATRSMN1; SMN2MAPT | |
| Isobutane SCHEMBL27575778 | 0.69 | KDM5B (0.37) | KDM4EKMT2APTGS2 | |
| SCHEMBL27643387 | 0.64 | SYK (0.39) | SYKBRD4SMN1; SMN2MAPTKMT2A | |
| SCHEMBL8185767 | 0.64 | MEN1 (0.46) | ATMKDM4EHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1304379-C | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO (JP) | 2007-03-14 | — | — | CN | disclosed |
| CN-1759103-A | Water-soluble phenylpyridazine derivative and medicine containing the same | KOWA CO (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1558903-A | Water-soluble phenylpyridazine derivative and drug containing the same | ������������ʽ���� | 2004-12-29 | — | — | CN | disclosed |