SCHEMBL27558142

SCHEMBL27558142

CC(N)(c1ccccc1)c1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.64
HTR2A P28223 2/20 0.44
HTR2C P28335 2/20 0.44
OPRK1 P41145 2/20 0.44
KCNH2 Q12809 2/20 0.44
ADRA1A P35348 1/20 0.44
KCNA3 P22001 2/20 0.41
TSHR P16473 4/20 0.41
MAPK1 P28482 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.40
CYP3A4 P08684 2/20 0.40
ALOX15 P16050 2/20 0.40
SLC6A2 P23975 2/20 0.40
CYP19A1 P11511 2/20 0.40
MEN1 O00255 1/20 0.40
SLC22A1 O15245 1/20 0.40
NR1I2 O75469 1/20 0.40
GMNN O75496 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27459558 0.80 KCNN4 (0.72) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL18827503 0.78 KCNN4 (0.57) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL1001586 0.78 KCNN4 (1.00) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL9577804 0.78 KCNN4 (0.57) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL31437177 0.78 KCNN4 (1.00) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL1431670 0.78 KCNN4 (0.56) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL31521320 0.78 KCNN4 (0.56) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL3669301 0.78 KCNN4 (0.56) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL11754835 0.77 KCNN4 (0.55) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL10510801 0.77 KCNN4 (0.42) KCNN4MAPK1MAPTKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100528828-C Production method of racemiation3-hydroxy-3- (2-phenylethyl) hexanoic acid C1-6 alkyl ester SUMIKA FINE CHEMICALS CO LTD (JP) 2009-08-19 CN disclosed
CN-1301244-C Process for producing -3-hydroxy-3- (2-phenylethyl) hexanoic acid and intermediates thereof SUMITOMO CHEMICAL CO (JP) 2007-02-21 CN disclosed
CN-1617846-A Process for producing -3-hydroxy-3- (2-phenylethyl) hexanoic acid and intermediates thereof SUMITOMO CHEMICAL CO (JP) 2005-05-18 CN disclosed