SCHEMBL9577804

SCHEMBL9577804

CC(C)(c1ccccc1)c1ccccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.57
HTR2A P28223 2/20 0.46
HTR2C P28335 2/20 0.46
OPRK1 P41145 2/20 0.46
KCNH2 Q12809 2/20 0.46
ADRA1A P35348 1/20 0.46
CYP3A4 P08684 3/20 0.45
ALDH1A1 P00352 2/20 0.45
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
TSHR P16473 3/20 0.44
KCNA3 P22001 2/20 0.43
MAPK1 P28482 2/20 0.42
LMNA P02545 2/20 0.42
ALOX15 P16050 2/20 0.42
MEN1 O00255 1/20 0.42
SLC22A1 O15245 1/20 0.42
NR1I2 O75469 1/20 0.42
GMNN O75496 1/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7571745 0.85 KCNN4 (0.48) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL2199266 0.83 ALDH1A1 (0.54) KCNN4CYP3A4ALDH1A1ESR1ESR2
SCHEMBL18827503 0.82 KCNN4 (0.57) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL11754835 0.80 KCNN4 (0.55) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL13018076 0.78 KCNN4 (0.53) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL27558142 0.78 KCNN4 (0.64) KCNN4HTR2AHTR2COPRK1KCNH2
Benzene SCHEMBL28296949 0.78 KCNN4 (0.52) KCNN4HTR2AHTR2COPRK1KCNH2
SCHEMBL10608720 0.78 CNR1 (0.41) KCNN4CYP3A4ALDH1A1ESR1ESR2
SCHEMBL26120875 0.76 ALDH1A1 (0.48) KCNN4CYP3A4ALDH1A1ESR1ESR2
SCHEMBL8157067 0.76 KCNN4 (0.61) KCNN4HTR2AHTR2COPRK1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5117215-A None JP disclosed
JP-H05117215-A SYNTHESIS OF 1-AMINOANTHRAQUINONE HOECHST CELANESE CORP 1993-05-14 JP disclosed
EP-0499451-A1 Synthesis of 1-amino-anthraquinone HOECHST CELANESE CORPORATION (US) 1992-08-19 EP disclosed
US-5132437-A From 2-Substituted Benzyl Compound and Xylene HOECHST CELANESE CORPORATION (US) 1992-07-21 US disclosed
US-4136123-A ALKALI METAL SULFONATE DERIVATIVES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-01-23 US disclosed