SCHEMBL27558237

SCHEMBL27558237

N#Cc1csc(CCBr)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5987097 0.85 CYP2A6 (0.37) CYP2A6
SCHEMBL5988110 0.77 CYP2A6 (0.37) CYP2A6
SCHEMBL27667806 0.69 RAB9A (0.36)
SCHEMBL23531541 0.69
SCHEMBL18430387 0.67 CYP2A6 (0.41) CYP2A6
SCHEMBL5988699 0.65 TSHR (0.30) CYP2A6
SCHEMBL27820619 0.63
SCHEMBL5987939 0.62 CYP2A6 (0.37) CYP2A6
SCHEMBL1365870 0.61 AR (0.36)
SCHEMBL6594590 0.60 CYP2A6 (0.36) CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1355810-A Prodrugs of thrombin inhibitors BASF AG (DE) 2002-06-26 CN disclosed
CN-1351609-A Low molecular weight complement protease inhibitors BASF AG (DE) 2002-05-29 CN disclosed
CN-1289341-A Thrombin inhibitors BASF AG (DE) 2001-03-28 CN disclosed