Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595115 | 0.86 | MEN1 (0.63) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL7487951 | 0.84 | CXCR1 (0.63) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL5594986 | 0.83 | MEN1 (0.69) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL6824079 | 0.83 | MEN1 (0.69) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL5595110 | 0.83 | KMT2A (0.60) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL7485664 | 0.81 | CXCR1 (0.67) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL7488086 | 0.80 | CXCR1 (0.63) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL7488285 | 0.80 | CXCR1 (0.66) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL5595104 | 0.79 | CXCR1 (0.80) | CXCR2MEN1KMT2ACXCR1TDP1 | |
| SCHEMBL5595118 | 0.77 | CXCR2 (0.74) | CXCR2MEN1KMT2ACXCR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1355697-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | CN | disclosed |