⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL189124 | 0.74 | CDK4 (0.35) | — | |
| SCHEMBL694594 | 0.71 | CDK4 (0.41) | — | |
| SCHEMBL443607 | 0.71 | PRKCI (0.44) | — | |
| SCHEMBL6231638 | 0.70 | HTR2C (0.33) | — | |
| SCHEMBL5777834 | 0.69 | MAPT (0.42) | — | |
| SCHEMBL5814894 | 0.69 | CDK4 (0.44) | — | |
| SCHEMBL16720401 | 0.69 | — | — | |
| SCHEMBL18422387 | 0.69 | — | — | |
| SCHEMBL16719574 | 0.68 | — | — | |
| SCHEMBL3198506 | 0.68 | GLO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101897662-B | Ophtalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent | NOVARTIS AG | 2013-05-22 | — | — | CN | disclosed |
| CN-101897662-A | The ophthalmic ointment compositions that comprises medicine, ointment base and solubilizing agent/dispersant | NOVARTIS AG | 2010-12-01 | — | — | CN | disclosed |
| CN-1674868-B | Ophthalmic ointment compositions comprising a drug, an ointment base and a solubilizer/dispersant | NOVARTIS AG | 2010-09-29 | — | — | CN | disclosed |
| CN-1297270-C | Ophthalmic composition comprising ascomycin | NOVARTIS AG (CH) | 2007-01-31 | — | — | CN | disclosed |
| CN-1674868-A | Ophthalmic ointment compositions comprising a drug, an ointment base and a solubilizer/dispersant | NOVARTIS AG (CH) | 2005-09-28 | — | — | CN | disclosed |
| CN-1638769-A | Ophthalmic compositions comprising ascomycin | NOVARTIS AG (CH) | 2005-07-13 | — | — | CN | disclosed |
| CN-1589144-A | Use of an ascomycin for the treatment of blepharitis | NOVARTIS AG (CH) | 2005-03-02 | — | — | CN | disclosed |
| CN-1411368-A | Method for producing liposome preparation | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-04-16 | — | — | CN | disclosed |
| CN-1342075-A | Liposome formulations | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-03-27 | — | — | CN | disclosed |