Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 5/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.31 |
| ▸ | ACHE | P22303 | 5/20 | 0.31 |
| ▸ | CLPP | Q16740 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557075 | 0.90 | KDM4E (0.32) | KDM4EITGB3ITGAV | |
| SCHEMBL27577324 | 0.90 | KDM4E (0.36) | KDM4EALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL27577338 | 0.89 | KDM4E (0.35) | KDM4EALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL27577414 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL27580818 | 0.86 | ITGB3 (0.44) | KDM4EALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL1069186 | 0.86 | ITGAV (0.47) | ITGB3ITGAV | |
| SCHEMBL28747036 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL27577314 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL27580887 | 0.81 | KDM4E (0.35) | KDM4EALDH1A1HPGDITGB3ITGAV | |
| SCHEMBL27577312 | 0.80 | ITGAV (0.35) | KDM4EALDH1A1ITGB3ITGAVLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1582166-A | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-02-16 | — | — | CN | claimed |
| CN-1541115-A | Smulaneous imaging of cardiac perfusion and vitronection receptor targeted imaging agent | ����˹�ж�-����˹˹����ҩƷ��˾ | 2004-10-27 | — | — | CN | claimed |
| CN-1356913-A | vitronectin receptor antagonist drugs | DU PONT PHARM CO (US) | 2002-07-03 | — | — | CN | claimed |
| CN-1582166-A | Vitronectin receptor antagonist pharmaceuticals for use in combination therapy | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-02-16 | — | — | CN | disclosed |
| CN-1541115-A | Smulaneous imaging of cardiac perfusion and vitronection receptor targeted imaging agent | ����˹�ж�-����˹˹����ҩƷ��˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1356913-A | vitronectin receptor antagonist drugs | DU PONT PHARM CO (US) | 2002-07-03 | — | — | CN | disclosed |