Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.62 |
| ▸ | ACHE | P22303 | 8/20 | 0.62 |
| ▸ | BACE1 | P56817 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
| ▸ | CCR2 | P41597 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558592 | 1.00 | BCHE (0.62) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL27558721 | 1.00 | BCHE (0.62) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL27558758 | 0.88 | BCHE (0.63) | BCHEACHEBACE1KMT2ADRD4 | |
| SCHEMBL27558651 | 0.88 | ACHE (0.63) | BCHEACHEBACE1CCR2ROCK2 | |
| SCHEMBL27558756 | 0.88 | BCHE (0.63) | BCHEACHEBACE1KMT2ADRD4 | |
| SCHEMBL27558650 | 0.88 | ACHE (0.63) | BCHEACHEBACE1CCR2ROCK2 | |
| SCHEMBL28747137 | 0.80 | TP53 (0.53) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL27558727 | 0.79 | ACHE (0.66) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL23507476 | 0.77 | BCHE (0.63) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL27558716 | 0.77 | CXCR4 (0.56) | BCHEACHEMEN1KMT2ACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1433402-A | Cycloamine CCR5 receptor antagonists | TEIJIN LTD (JP) | 2003-07-30 | — | — | CN | disclosed |
| CN-1384743-A | Remedies or preventives for diseases in association with chemokines | TEIJIN LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1376063-A | Cyclic amine CCR3 antagonisis | TEIJIN LTD (JP) | 2002-10-23 | — | — | CN | disclosed |