Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444854 | 0.81 | LMNA (0.57) | POLBSLC6A2ALDH1A1MAPK1SMN1; SMN2 | |
| Bromide SCHEMBL8855285 | 0.81 | DPP4 (0.50) | SSTR4NPC1RAB9AHDAC2HDAC8 | |
| SCHEMBL21058251 | 0.79 | ATM (0.52) | SSTR4NPC1RAB9AMAPTSLC6A2 | |
| SCHEMBL5608113 | 0.79 | SSTR4 (0.44) | SSTR4MAPTCASRADRB2ADRB1 | |
| SCHEMBL5358098 | 0.79 | FOLH1 (0.50) | ALDH1A1ADRB2CYP2C9 | |
| Bromide SCHEMBL8855394 | 0.78 | NPC1 (0.60) | NPC1RAB9AMAPTALDH1A1MAPK1 | |
| Bromide SCHEMBL11136046 | 0.78 | DPP4 (0.43) | SSTR4NPC1RAB9APOLBMAPT | |
| SCHEMBL7113803 | 0.76 | POLB (0.63) | SSTR4NPC1RAB9APOLBMAPT | |
| SCHEMBL10203428 | 0.75 | LMNA (0.63) | SSTR4NPC1RAB9APOLBMAPT | |
| SCHEMBL11876143 | 0.75 | TRPV1 (0.47) | SSTR4CASRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1328546-A | Pyrrolidines as Neuraminidase Inhibitors | ABBOTT LAB (US) | 2001-12-26 | — | — | CN | disclosed |