SCHEMBL27559347

SCHEMBL27559347

Cc1ccc(OP(=O)(O)O)c(C)c1.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 11/20 0.50
INPP5A Q14642 6/20 0.50
INPP5B P32019 2/20 0.50
AKT1 P31749 1/20 0.50
HPGD P15428 2/20 0.44
SRC P12931 2/20 0.41
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109597 0.98 INPPL1 (0.52) INPPL1INPP5AINPP5BAKT1HPGD
SCHEMBL497308 0.86 HPGD (0.45) HPGDLMNAPOLBTP53TDP1
SCHEMBL4131348 0.85 HPGD (0.44) HPGDLMNAPOLBTP53TDP1
SCHEMBL11085819 0.83 SRC (0.46) INPPL1INPP5AHPGDSRCLMNA
SCHEMBL8620844 0.82 INPPL1 (0.52) INPPL1INPP5AINPP5BAKT1SRC
SCHEMBL108984 0.82 CYP3A4 (0.50) HPGDLMNAPOLBTP53TDP1
SCHEMBL29349879 0.82 CYP3A4 (0.50) HPGDLMNAPOLBTP53TDP1
SCHEMBL16153098 0.81 INPPL1 (0.50) INPPL1INPP5AINPP5BAKT1HPGD
SCHEMBL28656347 0.81 INPPL1 (0.50) INPPL1INPP5AINPP5BAKT1SRC
SCHEMBL4126967 0.80 HPGD (0.44) HPGDLMNAPOLBTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710745-A Polypropylene polymer compositions with high stiffness characteristics 格雷斯公司 2021-11-26 CN disclosed
CN-106633327-B Polyethylene composition and film thereof 中国石油化工股份有限公司 2020-04-07 CN disclosed
CN-1300787-A Propylene ethylene block copolymer, resin composition and blown plastic articles IDEMITSU PETROCHEMICAL CO (JP) 2001-06-27 CN disclosed