Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MAPK6 | Q16659 | 4/20 | 0.44 |
| ▸ | MAPKAPK3 | Q16644 | 3/20 | 0.44 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052531 | 0.84 | MAPK1 (0.44) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK5 | |
| SCHEMBL28749489 | 0.83 | MAP2K4 (0.51) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK5 | |
| SCHEMBL7510671 | 0.81 | IKBKB (0.47) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK5 | |
| SCHEMBL27557921 | 0.81 | MAP2K4 (0.43) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK5 | |
| SCHEMBL1528566 | 0.80 | GAA (0.54) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK5 | |
| SCHEMBL27578364 | 0.78 | BACE1 (0.55) | MAPK1BACE1 | |
| SCHEMBL27579927 | 0.77 | IDO1 (0.56) | MAP2K4MAPK1MAPK6MAPKAPK3MAPKAPK5 | |
| SCHEMBL19035 | 0.74 | KMT2A (0.67) | MAPK1IKBKBBACE1NPC1 | |
| SCHEMBL27558026 | 0.73 | KDM4E (0.55) | MAPK1BACE1 | |
| SCHEMBL28319174 | 0.72 | POLB (0.44) | MAP2K4IKBKBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1346348-A | Amide compound and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-04-24 | — | — | CN | claimed |