Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GYS1 | P13807 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749489 | 0.87 | MAP2K4 (0.51) | IKBKBBACE1MAPK1MAPTGAA | |
| SCHEMBL27499014 | 0.86 | MAP2K4 (0.48) | IKBKBMAP3K14BACE1MAPK1ALOX12 | |
| SCHEMBL27557921 | 0.84 | MAP2K4 (0.43) | BACE1MAPK1MAPTGAAMEN1 | |
| SCHEMBL6052531 | 0.84 | MAPK1 (0.44) | BACE1MAPK1LMNAHPGDMAP2K4 | |
| SCHEMBL1528566 | 0.84 | GAA (0.54) | MAPK1NPSR1GAAMEN1KMT2A | |
| SCHEMBL8308326 | 0.83 | SIRT1 (0.45) | IKBKBMAP3K14GAASIRT1SIRT2 | |
| SCHEMBL27578364 | 0.82 | BACE1 (0.55) | BACE1MAPK1ALOX12MAPTGAA | |
| SCHEMBL27560751 | 0.81 | MAP2K4 (0.52) | IKBKBBACE1MAPK1MAP2K4MAPKAPK2 | |
| SCHEMBL27579927 | 0.81 | IDO1 (0.56) | BACE1MAPK1SIRT1MAP2K4MAPKAPK2 | |
| SCHEMBL27558026 | 0.77 | KDM4E (0.55) | BACE1MAPK1ALOX12MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | claimed |