Ethylbenzene

Ethylbenzene

SCHEMBL27560873

CC#N.CCc1ccccc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.74
CYP2A6 P11509 2/20 0.52
CYP1A2 P05177 3/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.41
CALM1 P0DP23 1/20 0.41
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
ATM Q13315 1/20 0.41
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL11874114 0.89 TP53 (0.93) TP53CYP2A6CYP1A2ALDH1A1CYP3A4
Ethylbenzene SCHEMBL27533703 0.89 TP53 (0.93) TP53CYP2A6CYP1A2ALDH1A1CYP3A4
Ethylbenzene SCHEMBL2091056 0.89
Ethylbenzene SCHEMBL28073274 0.87 TP53 (0.70) TP53CYP2A6CYP1A2ALDH1A1CYP1A1
Ethylbenzene SCHEMBL27390450 0.87 TP53 (0.70) TP53CYP2A6CYP1A2ALDH1A1CYP1A1
Ethylbenzene SCHEMBL27561282 0.87 TP53 (0.70) TP53CYP2A6CYP1A2ALDH1A1CYP1A1
Ethylbenzene SCHEMBL27500749 0.86 TP53 (0.88) TP53CYP2A6CYP1A2ALDH1A1CYP3A4
Ethylbenzene SCHEMBL28193346 0.86 TP53 (0.88) TP53CYP2A6CYP1A2ALDH1A1CYP3A4
Ethylbenzene SCHEMBL27427298 0.86 TP53 (0.88) TP53CYP2A6CYP1A2ALDH1A1CYP3A4
Ethylbenzene SCHEMBL27907671 0.86 TP53 (0.88) TP53CYP2A6CYP1A2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101148504-A Method for preparing polyepoxy alkane with middle or low molecular weight SHANGHAI CHEMICAL INST (CN) 2008-03-26 CN claimed
CN-103342662-B Method for synthesizing 2-alkylphenylacetonitrile NANTONG GOOD IDEA CHEMICAL TECHNOLOGY CO LTD 2015-01-14 CN disclosed
CN-103342662-A Method for synthesizing 2-alkylphenylacetonitrile NANTONG GOOD IDEA CHEMICAL TECHNOLOGY CO LTD 2013-10-09 CN disclosed
CN-101565388-B Preparation method of 2-aryl propionitrile compounds UNIV EAST CHINA NORMAL 2012-03-07 CN disclosed
CN-101565388-A Preparation method of 2-aryl propionitrile compounds UNIV EAST CHINA NORMAL (CN) 2009-10-28 CN disclosed
CN-101148503-A Preparation method of catalyst for ethylene oxide polymerization SHANGHAI CHEMICAL ACADEMY (CN) 2008-03-26 CN disclosed
CN-101148504-A Method for preparing polyepoxy alkane with middle or low molecular weight SHANGHAI CHEMICAL INST (CN) 2008-03-26 CN disclosed
CN-1310967-C Catalyst component for olefin polymerization reaction and its catalyst CHINA PETROCHEMICAL CORP (CN) 2007-04-18 CN disclosed
CN-1715301-A Catalyst component for olefin polymerization reaction and its catalyst CHINA PETROCHEMICAL CORP (CN) 2006-01-04 CN disclosed