Ethylbenzene

Ethylbenzene

SCHEMBL2091056

CCc1ccccc1.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Ethylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL11874114 1.00 TP53 (0.93)
Ethylbenzene SCHEMBL27533703 1.00 TP53 (0.93)
Ethylbenzene SCHEMBL27427298 0.97 TP53 (0.88)
Ethylbenzene SCHEMBL27500749 0.97 TP53 (0.88)
Ethylbenzene SCHEMBL28193346 0.97 TP53 (0.88)
Ethylbenzene SCHEMBL1331299 0.97
Ethylbenzene SCHEMBL3987542 0.97 TP53 (1.00)
Ethylbenzene SCHEMBL7458207 0.97 TP53 (1.00)
Ethylbenzene SCHEMBL11223212 0.97 TP53 (1.00)
Ethylbenzene SCHEMBL1330604 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118162072-A Recycling ethylbenzene liquid alkali washing and water washing device of ethylbenzene oxidation system 中石化南京工程有限公司 2024-06-11 CN claimed
CN-111995489-B System and method for treating tail gas of ethylbenzene oxidation reaction 中石化南京工程有限公司 2022-12-30 CN claimed
CN-109384669-A A kind of pyrethroid compound and its synthetic method and application 江苏扬农化工股份有限公司 2019-02-26 CN claimed
CN-106316991-A Application of titanium silicalite molecular sieve catalyst 青岛文创科技有限公司 2017-01-11 CN claimed
CN-104692995-A Process for producing benzene, methylbenzene and xylene from crude benzene ZHANHUA YUKAI NEW MATERIALS CO LTD 2015-06-10 CN claimed
EP-0226064-B1 IMPROVED DEHYDROGENATION PROCESS FOR PRODUCTION OF STYRENE FROM ETHYLBENZENE COMPRISING LOW TEMPERATURE HEAT RECOVERY AND MODIFICATION OF THE ETHYL-BENZENE-STEAM FEED THEREWITH Lummus Crest, Inc. (US) 1990-04-18 EP claimed
CN-86108265-A Produce cinnamic improvement dehydrogenating technology-the comprise improvement of low temperature recovery of heat and phenylethane-water vapor charging by phenylethane 1987-08-26 CN claimed
EP-0226064-A2 Improved dehydrogenation process for production of styrene from ethylbenzene comprising low temperature heat recovery and modification of the ethyl-benzene-steam feed therewith Lummus Crest, Inc. (US) 1987-06-24 EP claimed
US-4628136-A Dehydrogenation process for production of styrene from ethylbenzene comprising low temperature heat recovery and modification of the ethylbenzene-steam feed therewith LUMMUS CREST, INC. (US) 1986-12-09 US claimed
EP-0010455-B1 CRACKING PROCESS FOR PREPARING STYRENE CHEM SYSTEMS, Inc. (US) 1983-02-23 EP claimed
US-4250344-A Cracking process for styrene CHEM SYSTEMS INC. (US) 1981-02-10 US claimed
CN-114436744-B Method and system for preparing styrene by ethylbenzene dehydrogenation 中国石油化工股份有限公司 2024-06-28 CN disclosed
CN-114456037-B Raw material gasification method for preparing styrene by ethylbenzene dehydrogenation 中国石油化工股份有限公司 2024-06-28 CN disclosed
US-20240207755-A1 LOW-PRESSURE DROP ETHYLBENZENE EVAPORATOR AND ENERGY-SAVING PROCESS FOR ETHYLBENZENE VAPORIZATION IN STYRENE DEHYDROGENATION REACTION SYSTEM CHANGZHOU RUIHUA CHEMICAL ENGINEERING TECHNOLOGY CO., LTD. (CN) 2024-06-27 US disclosed
CN-118162072-A Recycling ethylbenzene liquid alkali washing and water washing device of ethylbenzene oxidation system 中石化南京工程有限公司 2024-06-11 CN disclosed
EP-0212334-A2 Improved polyimide formulation for forming a patterned film on a substrate International Business Machines Corporation (US) 1987-03-04 EP disclosed
US-4628136-A Dehydrogenation process for production of styrene from ethylbenzene comprising low temperature heat recovery and modification of the ethylbenzene-steam feed therewith LUMMUS CREST, INC. (US) 1986-12-09 US disclosed
US-4287375-A IN THE PRESENCE OF STEAM, WHEREIN HEAT FOR THE REACTION IS OBTAINED FROM A MELT OF SODIUM, POTASSIUM, AND LITHIUM CARBONATES METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) 1981-09-01 US disclosed
US-4237326-A SOLUTION OF METHYLATED BENZOQUINONE-4-OXIME MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1980-12-02 US disclosed
US-4052464-A FROM A KETONE AND TERT-BUTYL HYDROPEROXIDE, ACID CATALYST THE DOW CHEMICAL COMPANY (US) 1977-10-04 US disclosed