Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150436 | 0.76 | FOLH1 (0.42) | FOLH1TET2KDM4AKDM4CKDM2A | |
| SCHEMBL1231740 | 0.73 | CYP1A2 (0.50) | FOLH1TET2KDM4AKDM4CKDM2A | |
| SCHEMBL27935875 | 0.73 | TET2 (0.46) | FOLH1TET2KDM4AKDM4CKDM2A | |
| SCHEMBL5929523 | 0.72 | CYP1A2 (0.45) | FOLH1TET2KDM4AKDM4CKDM2A | |
| Ammonia Solution, Strong SCHEMBL29572919 | 0.71 | TET2 (0.44) | FOLH1TET2KDM4AKDM4CKDM2A | |
| SCHEMBL669817 | 0.65 | FOLH1 (0.64) | FOLH1TET2KDM4AKDM4CKDM2A | |
| SCHEMBL1751707 | 0.64 | — | — | |
| SCHEMBL535764 | 0.64 | — | — | |
| SCHEMBL1874484 | 0.64 | FOLH1 (1.00) | FOLH1TET2KDM4AKDM4CKDM2A | |
| SCHEMBL1752169 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1314882-A | NAALADase inhibitors and compositions as pharmaceutical compounds | GUILFORD PHARM INC (US) | 2001-09-26 | — | — | CN | disclosed |