Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561990 | 0.76 | FOLH1 (0.46) | FOLH1ENPEPANPEPCYP1A2GRM8 | |
| SCHEMBL4155771 | 0.73 | GRM8 (0.44) | FOLH1ENPEPANPEPCYP1A2GRM8 | |
| SCHEMBL22009103 | 0.70 | ARG1 (0.39) | ENPEPCYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL22009123 | 0.70 | ARG1 (0.39) | ENPEPCYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL16222763 | 0.67 | ARG1 (0.48) | ENPEPCYP1A2GRM2GRM3 | |
| SCHEMBL16222693 | 0.67 | ARG1 (0.48) | ENPEPCYP1A2GRM2GRM3 | |
| SCHEMBL27935875 | 0.67 | TET2 (0.46) | FOLH1CYP1A2GRM8GRM6GRIN2D | |
| SCHEMBL1231740 | 0.67 | CYP1A2 (0.50) | FOLH1CYP1A2GRM8GRM6GRIN2D | |
| SCHEMBL5929523 | 0.67 | CYP1A2 (0.45) | FOLH1CYP1A2GRM8GRM6GRIN2D | |
| Ammonia Solution, Strong SCHEMBL29572919 | 0.66 | TET2 (0.44) | FOLH1CYP1A2GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1933642-B1 | SALT ENHANCING COMPOUNDS AND USE | HOFMANN THOMAS FRANK (DE) | 2011-12-21 | — | — | EP | disclosed |
| US-20090155440-A1 | Salt Enhancing Compounds and Use | GIVAUDAN SA (CH) | 2009-06-18 | — | — | US | disclosed |
| EP-1933642-A1 | SALT ENHANCING COMPOUNDS AND USE | Thomas Frank Hofmann & Andreas Dunkel Inst. für Lebensmittelchemie (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042274-A1 | SALT ENHANCING COMPOUNDS AND USE | THOMAS FRANK HOFMANN & ANDREAS DUNKEL (DE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155440-A1 | Salt Enhancing Compounds and Use | TAS1R1, TAS2R41, TAS2R40 | FOLH1 651/4885ENPEP 830/4885ANPEP 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.