Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 10/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 4/20 | 0.40 |
| ▸ | EDNRB | P24530 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776089 | 0.92 | AGTR1 (0.44) | AGTR1LTB4R2ABCB11GP6EDNRA | |
| SCHEMBL27562149 | 0.90 | EDNRB (0.45) | EDNRAEDNRB | |
| SCHEMBL4764390 | 0.87 | AGTR1 (0.46) | AGTR1LTB4R2ABCB11GP6EDNRA | |
| SCHEMBL4771284 | 0.86 | AGTR1 (0.45) | AGTR1LTB4R2ABCB11GP6EDNRA | |
| SCHEMBL4771858 | 0.85 | AGTR1 (0.47) | AGTR1LTB4R2ABCB11GP6EDNRA | |
| SCHEMBL4773395 | 0.83 | AGTR1 (0.47) | AGTR1LTB4R2ABCB11GP6EDNRA | |
| SCHEMBL5528397 | 0.83 | AGTR1 (0.54) | AGTR1LTB4R2ABCB11GP6EDNRA | |
| SCHEMBL7849912 | 0.83 | AGTR1 (0.54) | AGTR1LTB4R2ABCB11GP6EDNRA | |
| SCHEMBL4775326 | 0.82 | EDNRA (0.54) | AGTR1EDNRAEDNRB | |
| SCHEMBL4774066 | 0.82 | AGTR1 (0.44) | AGTR1LTB4R2ABCB11GP6EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308536-A | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | BRISTOL MYERS SQUIBB CO (US) | 2001-08-15 | — | — | CN | claimed |