Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 9/20 | 0.40 |
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 5/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583278 | 0.89 | NR4A2 (0.39) | DYRK1AGSK3BDYRK1BNR4A2KDR | |
| SCHEMBL27563134 | 0.77 | MAP2K1 (0.56) | DYRK1AGSK3BCDK2GPR84 | |
| SCHEMBL20904626 | 0.74 | NR4A2 (0.40) | DYRK1AGSK3BDYRK1BNR4A2KDR | |
| SCHEMBL27583279 | 0.74 | DYRK1A (0.35) | DYRK1AKDM5ANR4A2 | |
| SCHEMBL12491378 | 0.73 | DYRK1A (0.49) | DYRK1AGSK3BNFATC1CDK2DYRK1B | |
| SCHEMBL27583266 | 0.73 | MAP2K1 (0.39) | GSK3BNR4A2KDRFLT3 | |
| SCHEMBL6780792 | 0.73 | TACR1 (0.47) | DYRK1AGSK3BCDK2DYRK1BGPR84 | |
| SCHEMBL2611046 | 0.73 | DYRK1A (0.51) | DYRK1AGSK3BNFATC1CDK2DYRK1B | |
| SCHEMBL1607800 | 0.73 | NR4A2 (0.62) | DYRK1AGSK3BNR4A2CPT1A | |
| SCHEMBL31753965 | 0.73 | NR4A2 (0.62) | DYRK1AGSK3BNR4A2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1404392-A | Antiviral azaindole derivatives | BRISTOL MYERS SQUIBB CO (US) | 2003-03-19 | — | — | CN | disclosed |