Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 4/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016302 | 0.84 | KMT2A (0.66) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL1897795 | 0.84 | KMT2A (0.66) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL31370083 | 0.84 | KMT2A (0.66) | KMT2AMEN1KDM4ELMNAMAPT | |
| Hydrochloric Acid SCHEMBL31407554 | 0.82 | TACR1 (0.43) | TACR1KMT2AMEN1KDM4ELMNA | |
| Tryptophan Methyl Ester SCHEMBL19161138 | 0.82 | MEN1 (0.70) | TACR1KMT2AMEN1KDM4ELMNA | |
| Tryptophan Methyl Ester SCHEMBL1195735 | 0.82 | MEN1 (0.70) | TACR1KMT2AMEN1KDM4ELMNA | |
| Tryptophan Methyl Ester SCHEMBL30180690 | 0.82 | MEN1 (0.70) | TACR1KMT2AMEN1KDM4ELMNA | |
| Tryptophan Methyl Ester SCHEMBL475267 | 0.82 | MEN1 (0.70) | TACR1KMT2AMEN1KDM4ELMNA | |
| Tryptophan Methyl Ester SCHEMBL122907 | 0.82 | MEN1 (0.70) | TACR1KMT2AMEN1KDM4ELMNA | |
| Tryptophan Methyl Ester SCHEMBL378072 | 0.81 | MEN1 (0.68) | TACR1KMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716852-B2 | FOR THERAPY OF ARTERIAL HYPERTENSION AND CARDIOVASCULAR DISEASES | LES LABORATORIES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | LES LABORATOIRES SERVIER (FR) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | MME, ACE, ECE1 | TACR1 1034/4885KMT2A 1603/4885MEN1 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.