Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 15/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 15/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27564788 | 0.88 | CDK2 (0.53) | CDK2CCNA2CCNA1CCNE1CDK5 | |
| SCHEMBL27564786 | 0.83 | CDK2 (0.47) | CDK2CCNA2CCNA1CCNE1CDK5 | |
| SCHEMBL5867719 | 0.74 | CDK2 (1.00) | CDK2CCNA2CCNA1CCNE1CDK5 | |
| SCHEMBL4314346 | 0.73 | CCNA2 (1.00) | CDK2CCNA2CCNA1 | |
| SCHEMBL28750548 | 0.73 | CCNE1 (0.57) | CDK2CCNA2CCNE1CDK5CDK5R1 | |
| SCHEMBL5867768 | 0.72 | CDK2 (0.74) | CDK2CCNA2CCNA1CCNE1CDK5 | |
| SCHEMBL5867894 | 0.72 | CDK2 (0.64) | CDK2CCNA2CCNA1CCNE1CDK5 | |
| SCHEMBL5867527 | 0.70 | CDK2 (0.75) | CDK2CCNA2CCNA1CCNE1CDK5 | |
| SCHEMBL5867579 | 0.70 | CDK2 (1.00) | CDK2CCNA2CCNA1CCNE1CDK5 | |
| SCHEMBL6385145 | 0.70 | CDK2 (0.90) | CDK2CCNA2CCNA1CCNE1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1373662-A | 3(5)-amino-pyrazole derivs., process for their preparation and their use as antitumor agents | PHARMACIA & UP JOHN S P A (IT) | 2002-10-09 | — | — | CN | claimed |
| CN-1373662-A | 3(5)-amino-pyrazole derivs., process for their preparation and their use as antitumor agents | PHARMACIA & UP JOHN S P A (IT) | 2002-10-09 | — | — | CN | disclosed |