Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729936 | 0.97 | NQO1 (0.44) | HPRT1NQO1KIF11TDP1L3MBTL1 | |
| Xanthone SCHEMBL27960792 | 0.92 | MAOA (0.49) | HPRT1NQO1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2089665 | 0.89 | HPRT1 (0.54) | HPRT1NQO1KIF11TDP1ALDH1A1 | |
| Chrysene SCHEMBL27616409 | 0.89 | HPRT1 (0.54) | HPRT1NQO1KIF11TDP1ALDH1A1 | |
| Phenanthrene SCHEMBL27372954 | 0.89 | HPRT1 (0.54) | HPRT1NQO1KIF11TDP1ALDH1A1 | |
| SCHEMBL30928215 | 0.89 | HPRT1 (0.54) | HPRT1NQO1KIF11TDP1ALDH1A1 | |
| SCHEMBL28077721 | 0.89 | HPRT1 (0.54) | HPRT1NQO1KIF11TDP1ALDH1A1 | |
| SCHEMBL27740850 | 0.89 | HPRT1 (0.54) | HPRT1NQO1KIF11TDP1ALDH1A1 | |
| SCHEMBL21176632 | 0.89 | HPRT1 (0.54) | HPRT1NQO1KIF11TDP1ALDH1A1 | |
| SCHEMBL31490440 | 0.87 | HPRT1 (0.52) | HPRT1NQO1KIF11TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | claimed |
| CN-101675060-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, their preparation and use | SANOFI AVENTIS | 2010-03-17 | — | — | CN | claimed |
| CN-108602807-A | Heterocycle sulfamide derivatives and drug containing it | EA制药株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-104841421-B | A kind of carbon monoxide-olefin polymeric, preparation method and prepare the method for o-phenyl phenol using it | 北京旭阳科技有限公司 | 2018-06-15 | — | — | CN | disclosed |
| CN-106701148-B | A kind of catalytic cracking process | 中国石油化工股份有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-107849029-A | Cyclopropane derivatives and drugs containing the same | EA制药株式会社 | 2018-03-27 | — | — | CN | disclosed |
| CN-106701148-A | Catalytic cracking process | 中国石油化工股份有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106458952-A | Heterocyclic sulfonamide derivative and medicine comprising same | EA制药株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-106336339-A | Production method for aromatic hydrocarbons | 中国石油化工股份有限公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-104841421-A | Catalyst composition and preparation method thereof, and method for preparing o-phenylphenol by using catalyst composition | BEIJING RISUN CHEMICALS TECHNOLOGY RES CO LTD | 2015-08-19 | — | — | CN | disclosed |
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |
| CN-100548299-C | Excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 2009-10-14 | — | — | CN | disclosed |
| CN-101407471-A | Compound capable of binding S1P receptor and pharmaceutical use thereof | ONO PHARMACEUTICAL CO (JP) | 2009-04-15 | — | — | CN | disclosed |
| CN-101333185-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-12-31 | — | — | CN | disclosed |
| CN-101333186-A | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO (JP) | 2008-12-31 | — | — | CN | disclosed |
| CN-101237885-A | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO (JP) | 2008-08-06 | — | — | CN | disclosed |
| CN-1893977-A | By EP4Medicine with agonist as active component for treating diseases related to bone loss | ONO PHARMACEUTICAL CO (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1882553-A | Phenylacetic acid derivative, process for producing the same, and use | ONO PHARMACEUTICAL CO (JP) | 2006-12-20 | — | — | CN | disclosed |
| CN-1856308-A | Excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1310716-A | Tricyclic sulfonamides and their derivatives as inhibitors of matrix metalloproteinases | WARNER LAMBERT CO (US) | 2001-08-29 | — | — | CN | disclosed |